Nekane Guarrotxena
Spanish National Research Council, Spain
Title: Encoded SERS plasmonic NPs in nanomedicine
Biography
Biography: Nekane Guarrotxena
Abstract
Single-molecule sensitivity of SERS has brought to prominence the special role played by so called SERS hotspots. Given that nanometer-scale junctions between nanoparticles produce significant electric field enhancement, the use of SERS-active dimers provides a suitable platform for developing effective sensing, imaging and therapy methodologies. Moreover, the relevant implementation of SERS active species design has opened new pathways and strategies for the SERS application in the clinical and medical field. Herein, I will present how encoded SERS metal NPs result promising multifunctional nanomaterials for biomedical applications. Particularly, SERS tag-synthesis, assembly and optical features will be stated and several examples of their use in detection, imaging, drug loading and therapy will be provided in order to show the remarkable and potential applicability in nanomedicine on the basis of their unique physicochemical features, sensitivity, selectivity and multiplexing capabilities.